Top 18 Collagen Serums for Microneedling You Need

Discover the best collagen serum for microneedling to boost your glow and cell renewal. Elevate your skincare game with our top picks tailored for radiant results.
BrandMy RatingPrice
Coera
Best Bang for Your Buck
8.6/10
Elastalift
Best for Skin Firming
8.6/10
Vt Cosmetics
Best for MicroNeedling Absorption
8.8/10
Zealsea
Best for Hydrating Skin
8.8/10
Eva Naturals
8.6/10

Best Collagen Serum for Microneedling

Unlock radiant, youthful skin with the perfect collagen serum tailored for microneedling sessions. Choosing the right serum can amplify your results, turning a simple treatment into a true glow-up. Dive into our expertly curated selection to find your skin’s new best friend.

Best Bang for Your Buck: Coera Collagen Peptide Serum

Coera Collagen Peptide Serum for Face | 4 fl oz | with Verisol | Professional Strength Formula for Women | Free of Parabens, SLS, & Fragrances | Packaging May Vary
Highlights
Moisturizes and nourishes
Absorbs quickly
Trusted, lab-tested ingredients

Coera's Collagen Peptide Serum delivers a refreshing, lightweight boost to your skin with its professional-strength formula.

Perfect for microneedling sessions, it deeply nourishes and hydrates without feeling greasy or heavy.

The quick absorption makes it ideal for layering post-treatment, helping to soften fine lines and improve skin elasticity over time.

While some users may crave more visible results immediately, the trusted lab-tested ingredients and generous volume make it a true value pick.

Plus, it's free of harmful additives, aligning with a clean beauty routine.

Be sure to also check out the best retinol serum korean for more options! Also, here is the price history so you know exactly when to buy!

Price history for Coera Collagen Peptide Serum on Amazon

Best for Skin Firming: Elastalift Collagen Serum

Elastalift Collagen Serum For Face | Collagen Face Serum For Skin Tightening Helps Lift, Plump, & Firm Sagging Skin | Serums For Skin Care | Anti Wrinkle Boost, Fragrance Free, 1.75 Fl Oz
Highlights
Plumps and firms skin
Safe for sensitive skin
Fast absorbing formula

Elastalift’s Collagen Lifting Serum truly lives up to its "best for skin firming" claim.

It’s designed specifically to help lift, plump, and tighten sagging skin—perfect for those looking to recapture that youthful glow.

We love how quickly it absorbs without leaving a greasy residue, making it a seamless addition to any routine.

Plus, its formulation is gentle enough for sensitive skin, packed with natural ingredients like soy and algae that support skin resilience.

While results do take some time, the visible firming benefits make this serum a solid choice in the anti-aging arsenal.

Be sure to also check out the best tallow balm for face wrinkles for more options! Also, here is the price history so you know exactly when to buy!

Price history for Elastalift Collagen Serum on Amazon

Best for MicroNeedling Absorption: VT Cosmetics Cica Reedle Shot

VT COSMETICS CICA Reedle Shot 300, Advanced Night Exosome, Microneedling Serum, Centella Asiatica, Hyaluronic Acid, Propolis, Soft Skin, Regeneration, Glass Skin, Korean Skin Booster 1.69Fl Oz (50ml)
Highlights
Enhances absorption
Smooths skin texture
Supports skin renewal

Reedle Shot is truly a game-changer for microneedling enthusiasts.

Its advanced exosome-coated technology maximizes nutrient absorption, making your skincare routine more effective than ever.

You might feel a slight tingling—don’t worry, it’s a good sign of active skin renewal—but it’s worth it for the boosted results.

Designed for all skin types, including sensitive skin, it works to smooth texture and support rejuvenation, leaving you with that coveted Korean glass skin glow.

Plus, using this as a step zero seamlessly integrates into your routine for instant, visible improvements.

An effortless addition for professional-level results at home!

Be sure to also check out the best facial oil for tightening skin for more options! Also, here is the price history so you know exactly when to buy!

Price history for VT Cosmetics Cica Reedle Shot on Amazon

Best for Hydrating Skin: ZealSea

Hyaluronic Acid Serum for Face, Hyrating Serum, Microneedling Serum, EWG Certified Zealsea for Sensitive Skin, Vegan Fragrance Free Non-Comedogenic Absorb Quickly, Pure Hyaluronic Acid Anti-Aging 1oz
Highlights
Deeply hydrates skin
Gentle for sensitive
Cruelty & chemical free

Zealsea's Ultimate Hydrating Serum is exceptionally good at delivering intense moisture, thanks to its powerful 4D Hyaluronic Acid.

It feels silky smooth upon application and immediately boosts skin’s elasticity—perfect for microneedling sessions where hydration is key.

It’s cruelty-free, fragrance-free, and safe for even sensitive skin, making it a versatile choice.

While it’s not the longest-lasting serum on the market and has a shorter shelf life, its clean ingredients and proven hydration benefits make it a top contender for anyone wanting a dewy, plump complexion.

Be sure to also check out the best facial cleanser for aging sensitive skin for more options! Also, here is the price history so you know exactly when to buy!

Price history for ZealSea on Amazon

Eva Naturals Collagen Peptide Serum

Collagen Peptide Serum - Anti Aging Collagen Serum for Face, Skin Brightening, Reduces Fine Lines & Wrinkles, Heals and Repairs Skin, Microneedling Serum with Hyaluronic Acid (2 oz)
Highlights
Skin firming effects
Hydrates and soothes
Affordable and effective

The Eva Naturals Peptide Complex Serum delivers noticeable skin-firming results by boosting collagen, helping to tighten and smooth the skin over time.

The formulation is packed with botanical ingredients like aloe vera, witch hazel, and jojoba, which hydrate and soothe for a calming finish—perfect for microneedling routines.

Plus, it’s clean, high-quality, and free from harmful additives, making it a safe choice for sensitive skin.

While results may vary, its affordability and gentle moisturizing benefits make it a stellar pick for those looking to enhance their skincare game without breaking the bank.

Be sure to also check out the best estriol face cream for wrinkles for more options! Also, here is the price history so you know exactly when to buy!

Price history for Eva Naturals Collagen Peptide Serum on Amazon

BRÜUN SC

BRÜUN SC - Control Stem Cell Ampoule - Micro Needling Korean Serum Booster for Face and Body to Use with and without Derma Pen Microneedling Skin Care Serum 1.18 fl.oz
Highlights
Effective for microneedling
Affordable and economical
Absorbs quickly

This 1.18 oz serum ampule is a game-changer for microneedling routines.

Its fast absorption makes it perfect for use with derma rollers and pens, delivering visible results without the fuss.

The serum is not only effective but also budget-friendly, helping you achieve a fresh, smooth, and attractive complexion without breaking the bank.

Plus, since it’s made in South Korea and cruelty-free, you can feel good about your choice.

While the ingredient list could be a bit more detailed, the overall performance and aesthetic boost make this serum a solid pick for your anti-aging arsenal.

Be sure to also check out the best retinol body cream for crepey skin for more options! Also, here is the price history so you know exactly when to buy!

Price history for BRÜUN SC on Amazon

COSRX Collagen Serum for Microneedling

COSRX 6X Peptide Collagen Booster Toner Serum, Niacinamide & Hyaluronic Acid Skin Renewal Boosting Facial Essence for All Skin Types, Korean Skin Care, Paraben Free, 150mL/5.07 Fl.Oz
Highlights
Visible firming effect
Deep hydration benefits
Layerable under makeup

The Skin Booster Toner from COSRX acts as a perfect first step, thanks to its lightweight, toner-like texture that absorbs immediately.

The star ingredients—6 potent peptides—work together to boost elasticity, smooth out fine lines, tighten pores, and deliver a radiant glow.

We noticed a visible firming effect after consistent use and appreciated how easily it layered under makeup and other products.

While some skin types might see different results, this serum offers deep hydration and a refreshing feel, making it a solid choice in your microneedling recovery routine.

Be sure to also check out the best collagen jelly for more options! Also, here is the price history so you know exactly when to buy!

Price history for COSRX on Amazon

Medicube Zero Exosome Shot

Medicube Zero Exosome Shot 2,000 PPM Spicule Facial Serum | Liquid Skin Booster Serum | Exosome, AHA+BHA+PHA | Pore Care, Dead Skin Cells, Skin Texture | Korean Skin Care 1.01 fl.oz
Highlights
Deep skin penetration
Excellent hydration boost
Clinically proven safety

The Exosome + Shot Booster from Medicube delivers deep into the skin thanks to its innovative micro-needle design coated with Exosomes — a true game-changer for microneedling support.

It offers superior hydration and enhances absorption by over 240%, meaning your skin drinks up those active ingredients quickly.

Plus, it’s clinically proven to be gentle on sensitive skin, so it’s suitable for daily use.

While some may experience mild discomfort during application, the full benefits of improved skin vitality make it worth it.

A smart addition for anyone serious about revitalizing their skin post-microneedling.

Be sure to also check out the best japanese retinol for more options! Also, here is the price history so you know exactly when to buy!

Price history for Medicube Zero Exosome Shot on Amazon

Yuree

Cosyuree Spicule Collagen Serum | 120,000 Micro Spicules for Glass Skin, Wrinkle Treatment & Hydration | Hyaluronic Acid Anti-Aging Serum (1.69 fl.oz.)
Highlights
Deep hydration boost
Visible skin improvement
Gentle for sensitive skin

The Cosyuree Collagen Spicule Serum delivers deep hydration thanks to its Hyaluronic Acid and collagen blend, instantly plumping and soothing the skin.

Its innovative micro collagen spicules enhance exfoliation and promote a glass-like, radiant glow.

Plus, it’s gentle enough for sensitive skin, making it suitable for daily use—day or night.

Though some users might experience a tingling sensation or minor redness, these are temporary signs of active rejuvenation.

With consistent application, this serum helps diminish fine lines and boosts skin elasticity, revealing a fresher, more youthful complexion.

Be sure to also check out the best face cream for menopause for more options! Also, here is the price history so you know exactly when to buy!

Price history for Yuree on Amazon

Eva Naturals Collagen Serum for Microneedling

Eva Naturals Trifecta Serum Bundle - Vitamin C Plus, Collagen Peptide Serum, Retinol Serum - Serum Set for Collagen Boost, Anti Aging & Youthful Glowing Skin
Highlights
Hydrates & Brightens
Botanical Ingredients
Clean & Effective

Eva Naturals' All-in-One Serum delivers a powerhouse of botanical hydration and brightening effects, making it perfect for microneedling routines.

The highly concentrated formula means you need only a few drops to see noticeable results, leaving your skin feeling nourished and glowing.

The inclusion of aloe vera, witch hazel, and rosehip seed oil provides soothing comfort and moisture, which is especially important post-microneedling.

However, the potent retinol might be too strong for sensitive skin, so patch testing is recommended.

Overall, it's a convenient, clean choice for boosting post-treatment radiance.

Be sure to also check out the best copper peptide cream for more options! Also, here is the price history so you know exactly when to buy!

Price history for Eva Naturals on Amazon

Advanced Clinicals Collagen Serum

Advanced Clinicals Collagen Serum For Face | Collagen Face Serum For Skin Tightening Helps Lift, Plump, & Firm Sagging Skin | Serums For Skin Care | Anti Wrinkle Boost, Fragrance Free, 1.75 Fl Oz
Highlights
Nourishing & Hydrating
Brightens & firms skin
Quick absorption

Advanced Clinicals Collagen Serum is a real treat for anyone seeking to boost their skin's bounce before microneedling.

Its rich, nourishing formula is packed with skin-loving ingredients like Vitamin C, Retinol, Shea Butter, and Manuka Honey that work together to hydrate and brighten, giving your face that plump, smooth, and youthful glow.

It absorbs quickly, making it perfect for a prep step.

While some might find it slightly thick, it’s an excellent addition to your routine if you want to target fine lines and sagging with a gentle powerhouse that supports collagen production.

Be sure to also check out the best face oils for wrinkles for more options! Also, here is the price history so you know exactly when to buy!

Price history for Advanced Clinicals Collagen Serum on Amazon

Jeu Demeure

Collagen, Peptide, Hyaluronic Acid Serum, Instant Face Lift Korean skin care Serum for Anti-Aging, Microneedling, Skin-Firming, Brightening, Hydrating for Face & Eye (without microneedle)
Highlights
Enhanced absorption for microneedling
Deep hydration with Hyaluronic Acid
Dermatologist-developed formula

The Jeu'Demeure DermiShuttle serum truly stands out with its breakthrough dermal delivery system, which ensures your skin absorbs maximum nutrients, especially after microneedling.

It’s rich in Hyaluronic Acid, providing deep hydration that leaves your skin feeling plump and revitalized.

Designed by dermatologists for sensitive skin, this formula is gentle yet powerful, helping to erase signs of aging like fine lines and puffiness.

While some may find it on the pricier side, the enhanced absorption and long-lasting hydration make it a worthy investment for those looking to boost skin elasticity and radiance.

Be sure to also check out the best estrogen face cream for more options! Also, here is the price history so you know exactly when to buy!

Price history for Jeu Demeure on Amazon

VOFEL Collagen Serum for Microneedling

Hyaluronic Acid Serum for Microneedling Serum Ampoules for Face BB Glow Starter Kit 0.35 oz 4 Vials
Highlights
Deep hydration boost
Enhances skin vitality
Suitable for all skin types

The VOFEL Hyaluronic Acid Serum delivers a powerful hydration boost that truly enhances skin vitality, making it look refreshingly plump and youthful.

Its professional-grade stem cell solution works in synergy with microneedling, amplifying results as if you've just stepped out of a salon.

Plus, it's suitable for all skin types, from sensitive to oily, and makes a thoughtful gift for skincare lovers.

The only caveat?

The ampoules are a bit fragile and may need handling with care.

Nevertheless, consistent use promises visible improvements over 28 days, revealing a radiant, firm complexion.

Be sure to also check out the best korean retinol serum for more options! Also, here is the price history so you know exactly when to buy!

Price history for VOFEL on Amazon

Theskcare

Anti Aging Apple Stem Cell Serum Ampoule for Face with Collagen,Hyaluronic Acid & Niacinamide,Rejuvenating Facial Serum for Fine Lines & Wrinkles,Plumping& Hydrating,30 Ampoules
Highlights
Hydrates & boosts glow
Suitable for sensitive skin
Travel-friendly packaging

The Advanced Anti-Aging Face Serum from THESKCARE delivers a luminous glow thanks to its powerful blend of Swiss Apple Stem Cells and Hydrolyzed Collagen.

It hydrates deeply with Niacinamide and Hyaluronic Acid, combating dryness while boosting skin elasticity.

The plant-based formulation feels lightweight and non-greasy—perfect for sensitive skin types.

Plus, the individually packaged ampoules make it incredibly portable, ideal for on-the-go skincare routines.

While it dries quickly and may be small for some, it’s a great choice for anyone seeking a hydrating, glow-boosting serum for microneedling sessions.

Be sure to also check out the best neck firming mask for more options! Also, here is the price history so you know exactly when to buy!

Price history for Theskcare on Amazon

Medicube PDRN Pink Serum

medicube PDRN Pink Collagen Exosome Shot Serum 7,500 PPM | Liquid Skin Booster | Exosome, Salmon DNA PDRN, Spicules | Uneven Skin Tone, Pore Care, Skin Texture | Korean Skin Care 1.01 fl.oz
Highlights
Effective skin rejuvenation
Good for hydration
Tingling, skin-boosting sensation

The Korean Glass Glow Skin serum from Medicube delivers a powerful punch of hydration and skin renewal in a lightweight, watery formula that feels delightful on the skin.

The inclusion of Salmon PDRN and Collagen works wonders to boost elasticity and promote a luminous glow, especially after microneedling sessions.

Plus, the spicule delivery system enhances absorption, ensuring active ingredients penetrate deeply.

However, be cautious—its intense tingling and potent ingredients can cause irritation for sensitive skin types.

With regular use, it can turn dull skin into a radiant, revitalized canvas.

Be sure to also check out the best neck cream for men for more options! Also, here is the price history so you know exactly when to buy!

Price history for Medicube PDRN Pink Serum on Amazon

WNP Collagen Serum Collagen Serum for Microneedling

collagen Serum Anti Aging,Oil-Suspension Serum|Barrier repair Firming Emergency Repair|WaterOilBalance| 4D hyaluronic acid|Single-Use Vials Skincare for Sensitiveskin(1.2ml/0.04 fl.oz.)*30
Highlights
Deep hydration
Multi-collagen support
Hydrating & smoothing

Its Innovative Suspension Oil Technology delivers a luxurious, water-oil fusion that infuses your skin with collagen peptides, squalane, and hyaluronic acid, offering deep hydration and a firming boost.

The 4D Hyaluronic Acid combined with three types of collagen works wonders on elasticity and wrinkles, leaving skin plump and smooth.

Plus, the potent blend of peptides and antioxidants actively fights fine lines, repairs DNA, and protects against environmental damage.

Whether used as a serum, primer, or mask enhancer, this versatile treatment provides spa-like results, albeit at a higher price point and with some users experiencing breakouts.

Be sure to also check out the best face tape for jowls for more options! Also, here is the price history so you know exactly when to buy!

Price history for WNP Collagen Serum on Amazon

The INKEY List

The INKEY List Collagen Peptide Serum, Face Serum to Help Reduce Appearance of Fine Lines and Wrinkles for Firmer-Looking Skin, For All Skin Types, 1.01 fl oz
Highlights
Hydrating and plumping
Smooths fine lines
Good value price

The INKEY List Collagen Peptide Serum delivers a delightfully hydrating boost, thanks to its blend of peptides like Matrixyl 3000 and Syn-Tacks.

It visibly plumps and firms skin, making fine lines appear softer after consistent use.

Plus, it’s suitable for all skin types, including sensitive skin—though some may experience dryness initially.

The serum applies smoothly and absorbs quickly, fitting perfectly into your morning and evening routines.

While early results are promising, expect some fluctuating effects as your skin adjusts.

Overall, a smart value choice for a youthful glow.

Be sure to also check out the best silicone masks for wrinkles for more options! Also, here is the price history so you know exactly when to buy!

Price history for The INKEY List on Amazon

CURECURE

Stem Cell Serum for Face, Microneedling Serum, Stem Cell Solution Ampoule to Use with and without Micro Needling, Anti Aging & Smooth Wrinkles 1.2 oz
Highlights
Enhances skin firmness
Deeply nourishes skin
Improves absorption with microneedling

The Stem Cell Serum by CURECURE truly lives up to its promises.

It activates damaged cells and boosts skin regeneration, giving your face a more youthful, vibrant glow.

Thanks to its rich antioxidant blend, it shields your skin from environmental stressors, helping to slow down the aging process.

When paired with microneedling, it enhances absorption and delivers noticeable improvements in firmness and smoothness.

While consistent use is key, this serum’s nourishing and hydrating properties make your skin feel irresistibly soft and plump.

Ultimately, it’s a solid choice for anyone seeking firmer, healthier skin post-treatment.

Be sure to also check out the best retinol for crepey skin for more options! Also, here is the price history so you know exactly when to buy!

Price history for CURECURE on Amazon

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