16 Estriol Face Creams for Wrinkles You Need to Know

Discover the best estriol face cream for wrinkles to rejuvenate your skin naturally. Uncover top picks for youthful, radiant results effortlessly.
BrandMy RatingPrice
Vigority
Great Budget Performer
8.8/10
Vigority
Great Budget Performer
8.8/10
Vigority
Great Budget Performer
8.8/10
Vigority
Best for Sensitive Skin
8.6/10
Biolabs Pro
8.6/10

Best Estriol Face Cream for Wrinkles

Discover the secret to maintaining luminous, youthful skin with the best estriol face cream for wrinkles—a game-changing weapon in your anti-aging arsenal. This potent formula works gently yet effectively, transforming tired, fine-lined complexions into radiant, plump canvases. Dive into our expertly curated selection and uncover how these creams can redefine your skincare routine with elegance and ease.

Great Budget Performer: Vigority Estriol Face Cream

Estriol Face Cream for Women: Natural Bioidentical Estrogen Cream with Wild Yam - For Menopause Relief, Hormone Balance & Skin Firmness - 3-Month Supply (4.23 Oz)
Highlights
Natural, nourishing ingredients
Reduces menopausal symptoms
Fast-absorbing, non-sticky

Vigority Estriol Face Cream offers comprehensive menopause relief while also supporting skin firmness and elasticity, making it a versatile pick for women navigating hormonal changes.

Packed with natural bioidentical estrogen and nourishing botanical extracts, it helps soothe hot flashes, night sweats, and skin sagging—all without stickiness or greasiness.

Although some users see mixed results with wrinkle reduction, its lightweight, fast-absorbing formula ensures daily comfort and hydration.

Best of all, at this price point, it provides long-lasting value, making it an excellent budget-friendly choice for those seeking visible benefits without breaking the bank.

Be sure to also check out the best face cream for menopause for more options! Also, here is the price history so you know exactly when to buy!

Price history for Vigority Estriol Face Cream on Amazon

Best for Sensitive Skin: Vigority Estrogen Cream

Estrogen Cream For Women, Natural Bioidentical, Hot Flashes Menopause Relief, Estrogen Cream With Wild Yam, Menstrual Cycle & Body Balance Support, Helps Reduce Hot Flashes, Paraben-Free, Vegan, 3-Month Supply(4 Oz)
Highlights
Smooth absorption, no residue
Reduces menopause symptoms
Gentle for sensitive skin

Vigority Estrogen Cream truly earns its spot as the best for sensitive skin.

Its vegan, cruelty-free formula contains natural ingredients like Wild Yam and cimicifuga racemosa root extract, making it gentle but effective.

The smooth absorption leaves no greasy residue, which is perfect for daily use—especially during menopause transition.

While its scent info is a bit limited and the tube is small, the cream's ability to reduce symptoms like hot flashes and irritability makes it a standout.

For women seeking a natural, safe hormone support, this spot-on solution is worth trying.

Be sure to also check out the best retinol body cream for crepey skin for more options! Also, here is the price history so you know exactly when to buy!

Price history for Vigority Estrogen Cream on Amazon

BIOLABS PRO Estriol Cream

BIOLABS PRO Natural Bioidentical Estriol Beauty Cream, Two Month Supply (3oz)
Highlights
Effective for hormonal balance
Good for epidermal plumpness
Fast absorption

… The BIOLABS PRO Estriol Face Cream delivers quick absorption, leaving your skin feeling smooth and hydrated in no time.

Its formulation is noted for supporting hormonal balance and boosting epidermal plumpness, which helps diminish those pesky wrinkles.

However, a bit of caution is advised—use sparingly and avoid over-application to prevent irritation.

The pump can be a little tricky sometimes, but the results make up for it.

Overall, if you're seeking a potent, fast-acting anti-aging cream, this one is definitely worth considering, especially for those prioritizing hormonal benefits.

Be sure to also check out the best neck cream for men for more options! Also, here is the price history so you know exactly when to buy!

Price history for BIOLABS PRO Estriol Cream on Amazon

SMNutrition Estriol Cream

Estrogen Estriol Cream | USP Micronized Estriol 175mg | Bioidentical Menopause & Menstrual Support | Soy, Gluten, Dairy, Cruelty, and Phenoxyethanol-Free Estrogen Cream | 84 Servings, 3.5oz Pump
Highlights
Supports hormone balance
Bioidentical and natural
Hygienic pump bottle

Estro-Life Cream by SMNutrition offers a well-balanced blend of micronized, bioidentical Estriol, ideal for supporting hormone health and reducing the appearance of wrinkles.

The hygienic pump bottle ensures a mess-free, controlled application, making it super convenient for daily use.

Plus, the inclusion of Vitamin A (Retinol) enhances skin renewal, which is a big bonus for anti-aging benefits.

While some users report mixed results, the product’s quality assurance—being third-party tested and non-GMO—gives us confidence in its safety and efficacy.

Overall, a natural, thoughtfully formulated choice for those seeking hormone support with skincare perks.

Be sure to also check out the best under eye primer for wrinkles for more options! Also, here is the price history so you know exactly when to buy!

Price history for SMNutrition Estriol Cream on Amazon

Bezwecken Estriol Face Cream for Wrinkles

Bezwecken - Transitions - 2oz Crème - Professionally Formulated Topical Wrinkle Treatment for Face & Neck - Safe, Natural, Paraben Free - 30 Day Supply
Highlights
Hydrates skin effectively
Reduces appearance of wrinkles
Gentle for sensitive skin

Transitions is a topical wrinkle treatment crème enriched with DHEA and Estriol, making it a natural choice for those seeking a gentle but effective boost.

Designed for nighttime use on the face and neck, it offers deep hydration while aiming to reduce the appearance of fine lines.

Plus, it's free from parabens, mineral oils, and animal products, aligning with clean beauty standards.

While some users may not see dramatic results within two months, its soothing formula makes it a safe and reliable option for sensitive skin.

Overall, a solid addition to your anti-aging routine!

Be sure to also check out the best eye cream for saggy eyelids for more options! Also, here is the price history so you know exactly when to buy!

Price history for Bezwecken on Amazon

Emerita

Emerita by Life-flo Estriol Cream with Vitamin E - Balancing Cream for Women at Midlife - with Soothing Aloe Vera and Sweet Almond Oil - Fragrance Free, 60-Day Guarantee, Not Tested on Animals, 4oz
Highlights
Smooth, lightweight texture
Nourishes and moisturizes
Trusted brand since 1978

The silky-smooth texture makes application a breeze, gliding effortlessly over skin without any greasy residue.

It’s enriched with the same vitamin-E boost as Pro-Gest Cream, providing nourishing moisture that leaves your face feeling soft and pampered.

While it doesn’t promise dramatic wrinkle reduction, its trusted brand since 1978 gives us confidence in its quality.

Keep in mind, the active ingredient level is on the lower side, so it’s best for maintenance rather than heavy-duty wrinkle targeting.

Overall, a gentle, nourishing choice for skin care buffs.

Be sure to also check out the best olay eye cream for dark circles for more options! Also, here is the price history so you know exactly when to buy!

Price history for Emerita on Amazon

Paula’s Choice

Paula’s Choice CLINICAL Phytoestrogen Elasticity Renewal Face Serum, Restores Loose, Thinning & Crepey-Looking Skin Due to Estrogen Loss, Fragrance-free & Cruelty-free, 1 Fl Oz.
Highlights
Visible skin improvements
Suitable for sensitive skin
Creamy, easy to apply

Paula's Choice offers a creamy, easy-to-apply formula that melts into the skin smoothly.

Many users report noticeable improvements in fine lines and wrinkles with consistent use.

Perfectly suited for those with sensitive skin, it’s gentle yet effective.

While the price can be steep, the quality makes it a worthwhile investment for serious anti-aging results.

Keep in mind, patience is key—like most quality skincare, results take time.

Overall, this serum is a reliable choice for visible glow and youthful radiance.

Be sure to also check out the best face tape for jowls for more options! Also, here is the price history so you know exactly when to buy!

Price history for Paula’s Choice  
on Amazon

Bealions Estriol Face Cream for Wrinkles

Retinol Cream Anti Aging for Face: Wrinkle Cream for Face Neck with Collagen Hyaluronic Acid - Night Moisturizer for Men Women - Facial Skin Care with Vacuum Pump for Exact Dosage
Highlights
Hydrates and plumps skin
Absorbs quickly, non-greasy
Suitable for all skin types

Bealions' estriol face cream is a powerhouse for anti-aging, blending Retinol, Collagen, Hyaluronic Acid, Vitamin C, and Vitamin E to target fine lines and wrinkles effectively.

It offers deep hydration without heaviness, leaving your skin feeling plump and refreshed.

Its light, fast-absorbing formula works well for all skin types—whether dry, oily, sensitive, or mature.

Plus, the hygienic pump ensures precise application every time.

Many users see visible improvements in just four weeks, making it a smart, quick fix for a youthful glow.

Be sure to also check out the best eye cream vitamin k for more options! Also, here is the price history so you know exactly when to buy!

Price history for Bealions on Amazon

Soulspa Pure Phytoestrogen Complex

Phytoestrogen Complex Estrogen Cream for Women Enrich with Coconut Oil & Shea Butter – Hydrating & Nourishing Topical Estrogen Cream for Face, Neck & Body 4 oz
Highlights
Hydrates dry skin
Quick absorption
Suitable for sensitive skin

The Hydration Rich Formula, powered by plant-based ingredients like Soy Isoflavones and Black Cohosh, offers a gentle yet effective way to support aging skin.

Its natural moisturizer blend of Coconut Oil and Shea Butter delivers deep hydration without the greasy afterfeel, making it a pleasure to use daily on the face and body.

We love how quickly it absorbs and leaves skin feeling firm, revived, and glowing.

Perfect for sensitive skin, this lightweight cream is a versatile addition to any anti-aging routine — truly a reliable choice for maintaining a youthful, revitalized look.

Be sure to also check out the best tallow balm for face wrinkles for more options! Also, here is the price history so you know exactly when to buy!

Price history for Soulspa Pure Phytoestrogen Complex on Amazon

Gold Bond Age Renew

Gold Bond Age Renew Tight & Firm Body & Face Lotion with Proteins & Lipids, Skin Firming Lotion for Aging, Dry Skin, 8 oz.
Highlights
Visible skin firming
Quick absorption
Hydrates skin effectively

Gold Bond Age Renew delivers clinically proven skin tightening and firming on both face and body, making it a versatile choice.

Its unique skin-firming complex with proteins and lipids works to diminish saggy skin, while its 24-hour hydration keeps skin plump and moisturized without feeling greasy.

The quick absorption and dermatologist-tested formula make it a reliable option for daily use.

However, it’s worth noting that some users might experience breakouts, and those hoping for added scent variety might be disappointed.

Overall, it’s a solid, hydrating firming lotion for aging skin.

Be sure to also check out the best korean anti wrinkle cream for more options! Also, here is the price history so you know exactly when to buy!

Price history for Gold Bond Age Renew on Amazon

SimplyVital Estriol Face Cream for Wrinkles

SimplyVital Collagen, Retinol & Hyaluronic Acid Cream - Anti-Aging Face Moisturizer for Face, Neck & Décolleté - Made in USA, Daily Moisturizer Face Cream - 1.7 fl.oz.
Highlights
Effective hydration boost
Smooth, silky texture
No waste packaging

This nourishing face moisturizer delivers a gentle yet effective boost of hydration that leaves skin feeling silky smooth and comfortably plump.

Its collagen-enhanced formula helps improve skin’s firmness and elasticity, giving your face and neck a more youthful, vibrant glow.

Although the rich texture may be best suited for evening routines or dry skin types, we love how easily it absorbs without any greasy residue.

Just a heads-up—packaging can sometimes crack, and results will vary, but overall, this cream is a potent, USA-made choice for supporting your anti-aging goals.

Be sure to also check out the best cc cream for mature skin over 50 for more options! Also, here is the price history so you know exactly when to buy!

Price history for SimplyVital on Amazon

ATAZUA Estrogen Cream

Estrogen Cream, Natural Formula Estrogen Cream, Body Balance Support
Highlights
Plant-based formula
Gentle yet effective
Improves skin tightness

The ATAZUA Estrogen Cream offers a plant-based formula that's both gentle and effective—perfect for those seeking a natural solution.

It works to restore skin tightness and bring back that youthful bounce, especially around midlife.

The lightweight, easy-to-apply texture makes it a breeze to integrate into your daily routine.

While it comes in a small jar and might require consistent application, the customer rating of 5 stars speaks volumes about its efficacy.

For those prioritizing safety and simplicity, this cream is definitely worth considering.

Be sure to also check out the best facial cleanser for aging sensitive skin for more options! Also, here is the price history so you know exactly when to buy!

Price history for ATAZUA Estrogen Cream on Amazon

YTDB

Advanced Neck Firming Cream – 3% Retinol & Hyaluronic Acid for Wrinkle Reduction, Lifting & Skin Tightening – Anti-Aging Moisturizer for Face, Neck & Décolleté – Deep Hydration, 1.7 FL OZ
Highlights
Lightweight, fast-absorbing
Gentle for sensitive skin
Visible firming results

The ULTIMATE ANTI-AGING FORMULA truly lives up to its name.

It’s lightweight and absorbs quickly, making it a joy to apply without any greasy residue.

The blend of retinol, collagen, and vitamin C works synergistically to smooth out fine lines and boost elasticity—especially around the delicate neck area.

We love how hydrating hyaluronic acid and luxurious ingredients like Cupuacu butter leave the skin feeling plump and nourished.

Plus, its gentle, organic formulation makes it suitable even for sensitive skin types.

Consistent use reveals a more youthful, firm appearance—definitely a standout in our lineup!

Be sure to also check out the best cream for vertical lip lines for more options! Also, here is the price history so you know exactly when to buy!

Price history for YTDB on Amazon

Eclat Skincare Estriol Face Cream for Wrinkles

Collagen Anti Aging Face Cream with Patented Matrixyl-3000 & Argireline - 5x More Powerful w/ Pep-Boost Peptide Complex + 10 Antioxidants - Facial Wrinkle Day/Night Cream Face Moisturizer for Women
Highlights
Improves fine lines
Deep hydration boost
Supports collagen production

This advanced anti-aging formula packs a punch with natural antioxidants and peptides that noticeably reduce fine lines and wrinkles.

Its light, thin consistency allows for quick absorption, perfect for those busy mornings.

Plus, the powerful peptide complex, including Argireline and Matrixyl 3000, helps boost collagen production for a firmer, more youthful glow.

While some users may find it a tad sensitive or not as deeply moisturizing as thicker creams, the deep hydration and radiance it delivers make it a go-to for revitalizing tired skin.

Be sure to also check out the best face mask for forehead wrinkles for more options! Also, here is the price history so you know exactly when to buy!

Price history for Eclat Skincare on Amazon

EnaSkin

EnaSkin Retinol Cream for Wrinkles: Face Neck Collagen Cream for Tightening Skin - Anti Aging Facial Moisturizer Day and Night for Women and Men 1.7 Fl OZ
Highlights
Hydrates and Moisturizes
Effective Anti-Aging Results
Gentle, No Irritation

EnaSkin's Retinol Anti-Aging Cream provides deep hydration thanks to its powerful 4D hyaluronic acid, leaving the skin feeling soft, plump, and elastic.

Its formula works diligently to tighten skin and reduce the appearance of wrinkles, making it a solid choice for aging concerns.

Plus, it’s gentle enough for all skin types, so everyone can enjoy smoother, more radiant skin.

Keep in mind, consistent use is key, and results might take some time to fully show.

Overall, a reliable, nourishing option for those targeting signs of aging with grace.

Be sure to also check out the best makeup to cover up wrinkles for more options! Also, here is the price history so you know exactly when to buy!

Price history for EnaSkin on Amazon

HelloPharmacist Bioidentical Bi-EST 5.0

Bioidentical Bi-EST 5.0 Estrogen Menopause Relief Cream for Women - 5 mg Per Pump - Preserved with Essential Oils and Herbs - Additional Moisturizers for Skin Nourishment (3 oz/85g)
Highlights
Fast absorption, no residue
High-quality bioidentical ingredients
Effective relief from hot flashes

Estrogen Menopause Relief Cream boasts USP-grade, bioidentical ingredients that closely mimic your body's natural hormones, offering gentle yet effective relief.

With a precise 5mg dose per pump, it ensures consistent hormone regulation—just the way you need it.

The cream’s smooth texture absorbs rapidly, leaving no greasy residue behind, making it a breeze to apply on your inner arms, thighs, or chest.

Plus, the use of essential oils and herbs gives it a natural touch without harsh chemicals.

While the scent isn’t scent-free and the pump can be quirky, its rapid action and high-quality formulation make it a favorite for those seeking quick menopausal relief and skin hydration.

Be sure to also check out the best over the counter eye cream for crow's feet for more options! Also, here is the price history so you know exactly when to buy!

Price history for HelloPharmacist Bioidentical Bi-EST 5.0 on Amazon

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